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Allele : Nlrp4f<em1Lil> NLR family, pyrin domain containing 4F; endonuclease-mediated mutation 1, Lei Li

Primary Identifier  MGI:6393576 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Nlrp4f
Strain of Origin  CD-1 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing technology was used to generate a 62 bp deletion in exon 2, including the start codon. qRT-PCR, immunoblot analysis and immunofluorescent staining confirmed the absence of endogenous transcript and encoded protein in oocytes from homozygous null females.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Nlrp4f<->,
  • Nlrp4f<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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3 Publication categories

Trail: Allele