|  Help  |  About  |  Contact Us

Allele : Unkl<em1(IMPC)J> unkempt family like zinc finger; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6394011 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Unkl
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GTACAGCAGTTATAGCCCGA and AATGGCTCACGGTTAGCAGT, which resulted in a 299 bp deletion beginning at Chromosome 17 position 25,201,004 bp and ending after 25,201,302 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001293958 (exon 4) and 165 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 155 and early truncation 1 amino acids later.
  • mutations:
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele