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Allele : Wdr53<em1(IMPC)J> WD repeat domain 53; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6394015 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Wdr53
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTCAAAAAGCCCGTCCTGTT and GTATCCCCTAAATGAGCTTT, which resulted in a 559 bp deletion beginning at Chromosome 16 position 32,256,492 bp and ending after 32,257,050 bp (GRCm38/mm10). This mutation deletes 559 bp from ENSMUSE00000130400 (exon 3) and is predicted to cause a change of amino acid sequence after residue 171 and early truncation 12 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories