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Allele : Dmd<em#Tve> dystrophin, muscular dystrophy; endonuclease-mediated mutation, Tatiana V Egorova
Primary Identifier  MGI:6394017 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Dmd
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology deleted exons 8-34 using two sgRNAs 5'-TGATCTGTTGGGTCTTCG(GGG)-3' and 5'-GTGGCAGACTAGTAGTTTG(AGG)-3'. This deletion recapitulates a large de novo deletion of these exons in a Russian Duchenne muscular dystrophy patient. The pound symbol (#) is used for the pool of founders 35, 40, 64, and 101.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • DMD<del8-34>,
  • DMD<del8-34>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories





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