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Allele : Ehd2<tm1.1Cbm> EH-domain containing 2; targeted mutation 1.1, Carmen Birchmeier

Primary Identifier	MGI:6394087	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Ehd2
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 3. A neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Cre-mediated recombination removed exon 3 and the selection cassette.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Ehd2<del>,
Ehd2<del>

earliestPublication:
Matthaeus C, et al. (2019) eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization. PLoS One 14(10):e0223620

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

8 Publication categories

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