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Allele : Bard1<tm3.1Rjbr> BRCA1 associated RING domain 1; targeted mutation 3.1, Richard J Baer

Primary Identifier  MGI:6399953 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bard1
Transmission  Germline Strain of Origin  (C57BL/6J x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A glutamine to X nonsense mutation at amino acid 552 (Q552X) was inserted into exon 7 and a loxP-flanked PKG-neomycin resistance gene cassette was inserted into intron 6. The selection cassette was removed via cre-mediated recombination. Western blot analysis shows that a truncated protein is not detected in mouse embryonic fibroblasts.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Bard1<Q552X>,
  • Bard1<Q552X>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories