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Allele : Yap1<tm1.2Eno> yes-associated protein 1; targeted mutation 1.2, Eric N Olson

Primary Identifier	MGI:6403855	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Yap1
Transmission	Germline	Strain of Origin	129S/SvEv
Is Recombinase	false	Is Wild Type	false

molecularNote

One loxP site was inserted in intron 2 while an FRT flanked PGK-neo selection cassette followed by a second loxP site was inserted in intron 3. Subsequent excision of the selection cassette left exon 3 flanked by loxP sites. Cre-mediated recombination removed exon 3.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Frum T, et al. (2019) TEAD4, YAP1 and WWTR1 prevent the premature onset of pluripotency prior to the 16-cell stage. Development 146(17):dev179861

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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