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Allele : H2az1<em1(IMPC)J> H2A.Z variant histone 1; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6403860 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  H2az1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCCAATGGGAGAACGCACAG and GTACTTTCGTTGTACCCTGA, which resulted in a 2664 bp deletion beginning at Chromosome 3 position 137,864,450 bp and ending after 137,867,113 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000669244, ENSMUSE00001255094, ENSMUSE00001280001, ENSMUSE00001260075, ENSMUSE00000635681 (exons 1-5) and 1575 bp of flanking intronic sequence including the splice acceptor, donor and start site. This deletion is predicted to generate a null allele.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele