Primary Identifier | MGI:6423421 | Allele Type | Endonuclease-mediated |
Gene | Slxl1 | Strain of Origin | mixed |
Is Recombinase | false | Is Wild Type | false |
description | Zygotes were derived from a cross of (C57BL/6NHsd x DBA/2NHsd)F1 and C57BL/6NHsd. |
molecularNote | To generate mice with multi-megabase duplication of Slxl1 ampliconic region, loxP sites were sequentially integrated upstream and downstream of the Slxl1 ampliconic region via CRISPR. Cre-mediated recombination duplicated the floxed allele. |