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Allele : Slxl1<em1.2Jbmu> Slx-like 1; endonuclease-mediated mutation 1.2, Jacob Mueller

Primary Identifier  MGI:6423421 Allele Type  Endonuclease-mediated
Gene  Slxl1 Strain of Origin  mixed
Is Recombinase  false Is Wild Type  false
description  Zygotes were derived from a cross of (C57BL/6NHsd x DBA/2NHsd)F1 and C57BL/6NHsd.
molecularNote  To generate mice with multi-megabase duplication of Slxl1 ampliconic region, loxP sites were sequentially integrated upstream and downstream of the Slxl1 ampliconic region via CRISPR. Cre-mediated recombination duplicated the floxed allele.
  • mutations:
  • Insertion,
  • Duplication
  • synonyms:
  • Slxl1<Dup>,
  • Slxl1<Dup>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories