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Allele : Pax6<em4Ems> paired box 6; endonuclease-mediated mutation 4, Elizabeth M Simpson

Primary Identifier  MGI:6423491 Allele Type  Endonuclease-mediated
Attribute String  Epitope tag Gene  Pax6
Strain of Origin  B6.Cg-Pax6<em1Ems>/EmsMmmh Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR-targeting of zygotes carrying Pax6em1Ems corrected the Pax6Sey by introducing a T to G point mutation restoring the wild-type sequence. An additional G to A mutation was introduced further downstream.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • FeyCor<em4>,
  • Pax6<Fey-em4(c.[580TG;591GA])Ems>,
  • Pax6<Fey-em4(c.[580TG;591GA])Ems>,
  • FeyCor<em4>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories