|  Help  |  About  |  Contact Us

Allele : Stk39<tm1.1Pawe> serine/threonine kinase 39; targeted mutation 1.1, Paul A Wellling

Primary Identifier  MGI:6423628 Allele Type  Targeted
Attribute String  Constitutively active, Epitope tag Gene  Stk39
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP flanked PGK-neomycin selection cassette and an HA-tagged Stk39 cDNA containing two mutations, a threonine to glutamate change at residue 243 (T243E) and a serine to aspartate change at 383 (S383D), and an in-frame stop codon were inserted after the start codon of Stk39. Cre-mediated recombination excised the selection cassette resulting in expression of the constitutively active kinase under the control of the native gene promoter.
  • mutations:
  • Nucleotide substitutions
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories