| Primary Identifier | MGI:6429840 | Allele Type | Targeted |
| Attribute String | Inducible, Inserted expressed sequence, Reporter | Gene | Gt(ROSA)26Sor |
| Transmission | Germline | Strain of Origin | Not Specified |
| Induced With | doxycycline/tetracycline | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgenic construct inserted into the GT(ROSA)26Sor locus contains a splice-acceptor sequence, loxP-flanked neomycin selection cassette, a tetracycline transactivator (tTA) gene, insulator sequence, CMV promoter responsive to tTA, rabbit -globin intron, Mtor cDNA encoding a kinase dead protein, an internal ribosome entry site, and an enhanced green fluorescence protein (EGFP) cDNA. Expression of the tetracycline transactivator is turned on upon Cre-mediated recombination, and removal of the neomycin selection cassette induces Mtor expression in the absence of doxycycline. |
