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Allele : Tdp1<em1(IMPC)Tcp> tyrosyl-DNA phosphodiesterase 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Primary Identifier  MGI:6414506 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Tdp1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele from project TCPR1537 was generated at The Centre for Phenogenomics by electroporatingCas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of AATTCCGTGATGGGAGTTGT targeting the 5' side and ACAGGGCTTTTGTCGGATCT targeting the 3' side of a critical region. This resulted in a 1137-bp deletion; Chr12:99909519-99910655 (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories





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