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Allele : Ccr2<em1(icre/ERT2)Peng> C-C motif chemokine receptor 2; endonuclease-mediated mutation 1, Bo Peng
Primary Identifier  MGI:6414749 Allele Type  Endonuclease-mediated
Attribute String  Inducible, Recombinase, Reporter Gene  Ccr2
Strain of Origin  C57BL/6N Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  Plasmids encoding a guide RNA was designed to insert a improved icre-ER fusion gene (an iCre recombinase fused to a human estrogen receptor ligand binding domain) between exon 3 and the 3' UTR of the chemokine (C-C motif) receptor 2 (Ccr2) gene. An enhanced green fluorescent protein (EGFP) sequence was inserted downstream of the icre-ER, and viral P2A oligopeptides, from porcine teschovirus-1, flank the icre-ER fusion gene to mediate ribosomal skipping.
  • mutations:
  • Insertion
  • synonyms:
  • CCR2-CreER-GFP,
  • CCR2-CreER-GFP
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0 Expresses

0 Mutation Involves

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Mouse alleles --> Mammalian phenotypes (MP terms)

 

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