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Allele : Wnk4<em1Cjc> WNK lysine deficient protein kinase 4; endonuclease-mediated mutation 1, Chih-Jen Cheng

Primary Identifier  MGI:6414871 Allele Type  Endonuclease-mediated
Gene  Wnk4 Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR-Cas9 technology generated a CTC to TTC change resulting in a leucine to phenylalanine substitution at amino acid 319 and a CTG to TTC change resulting in a leucine to phenylalanine substitution at amino acid 321. The L319F/L321F mutations result in a chloride-insensitive WNK4.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • L319F/L321F WNK4 KI,
  • L319F/L321F WNK4 KI
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories