Primary Identifier | MGI:6416441 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Fgfr3 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A human FGFR3 cDNA (NM_000142) with a glycine to arginine substitution at amino acid 380 (G380R), a FRT-flanked neomycin selection cassette, and a loxP site replaced a part of exon 2 to exon 17 of the mouse gene. Flp-mediated recombination removed the neomycin selection cassette. |