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Allele : Cfap69<em1Fzh> cilia and flagella associated protein 69; endonuclease-mediated mutation 1, Feng Zhang

Primary Identifier	MGI:6431857	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Cfap69
Strain of Origin	C57BL/6J	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR/Cas9 technology deleted exons 2-4, resulting in a frameshift mutation.

mutations:
Intragenic deletion

earliestPublication:
He X, et al. (2019) Novel homozygous CFAP69 mutations in humans and mice cause severe asthenoteratospermia with multiple morphological abnormalities of the sperm flagella. J Med Genet 56(2):96-103

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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