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Allele : Syk<tm2.1Mrl> spleen tyrosine kinase; targeted mutation 2.1, Merck Research Laboratory

Primary Identifier	MGI:6434795	Allele Type	Targeted
Attribute String	Not Specified	Gene	Syk
Transmission	Germline	Strain of Origin	C57BL/6NTac
Is Recombinase	false	Is Wild Type	false

molecularNote

The K396R point mutation has been introduced into exon 10. The positive selection marker (Puromycin resistance - PuroR) was flanked by FRT sites and inserted into intron 9. The constitutive point mutation allele was generated after Flp-mediated recombination

mutations:
Insertion,
Single point mutation

cellLines:
Not Specified

earliestPublication:
Taconic (2006) Information obtained from Taconic website. MGI Direct Data Submission

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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