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Allele : Rock1<tm2.1Mrl> Rho-associated coiled-coil containing protein kinase 1; targeted mutation 2.1, Merck Research Laboratory
Primary Identifier  MGI:6435112 Allele Type  Targeted
Attribute String  Not Specified Gene  Rock1
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  The K105A point mutation was introduced into exon 4. The positive selection marker (Puromycin resistance - PuroR) was flanked by FRT sites and inserted into intron 4. The constitutive point mutation allele was generated after Flp-mediated recombination.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Rock1<tm1.1(K105A)Mrl>,
  • ROCK1<KD>,
  • ROCK1<KD>,
  • Rock1<tm1.1(K105A)Mrl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories





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