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Allele : Tubb4a<em1Avan> tubulin, beta 4A class IVA; endonuclease-mediated mutation 1, Adeline Vanderver

Primary Identifier  MGI:6444834 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Tubb4a
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a G to A change at position 745 (c.745G>A) resulting in an aspartate to asparagine substitution at amino acid 249 (p.D249N) in exon 4. An off-target effect includes one synonymous mutation in cis at p.Lys244Lys (c.732C>A).
  • mutations:
  • Single point mutation
  • synonyms:
  • Tubb4a<D249N>,
  • Tubb4a<D249N>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories