Primary Identifier | MGI:6444834 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Tubb4a |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated a G to A change at position 745 (c.745G>A) resulting in an aspartate to asparagine substitution at amino acid 249 (p.D249N) in exon 4. An off-target effect includes one synonymous mutation in cis at p.Lys244Lys (c.732C>A). |