Primary Identifier | MGI:6445626 | Allele Type | Transgenic |
Attribute String | Inducible | Gene | Tg(tetO-Btnl1)#Ahay |
Strain of Origin | C57BL/6N-Btnl1<tm1(KOMP)Mbp> | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The cDNA for exons 2-9 and the coding part of exon 10, comprising the entire coding region plus part of the 5' UTR, was placed downstream of a tetracycline response element (TRE) and minimal CMV promoter, followed by beta-globin intron and poly signal sequences. Expression of this transgene can be controlled by tetracycline/doxycycline in conjunction with a tTA or rtTA expressing allele. The transgene construct was injected into blastocysts homozygous for the
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