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Allele : Tg(tetO-Btnl1)#Ahay transgene insertion, Adrian C Hayday

Primary Identifier  MGI:6445626 Allele Type  Transgenic
Attribute String  Inducible Gene  Tg(tetO-Btnl1)#Ahay
Strain of Origin  C57BL/6N-Btnl1<tm1(KOMP)Mbp> Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The cDNA for exons 2-9 and the coding part of exon 10, comprising the entire coding region plus part of the 5' UTR, was placed downstream of a tetracycline response element (TRE) and minimal CMV promoter, followed by beta-globin intron and poly signal sequences. Expression of this transgene can be controlled by tetracycline/doxycycline in conjunction with a tTA or rtTA expressing allele. The transgene construct was injected into blastocysts homozygous for the function showMoreInlineList(listDiv) { jQuery(listDiv + ' ul li').each(function(index) { if (!jQuery(this).is(":visible")) { jQuery(this).show(); } }); jQuery(listDiv + ' ul li.show-more').hide(); } function applyShowMoreInlineList(listDiv, listLength) { jQuery(listDiv + ' ul li').each(function(index) { listLength -= jQuery(this).text().length; if (listLength <= 0) { jQuery(this).hide(); } }); if (listLength <= 0) { jQuery('
  • ', { 'class': 'show-more', 'html': jQuery('', { 'href': '#', 'title': 'Show more items', 'text': 'Show more', 'click': function(e) { showMoreInlineList(listDiv); e.preventDefault(); } }) }).appendTo(listDiv + ' ul'); } }
    • mutations:
    • Insertion
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    1 Feature

    Trail: Allele

    Genome

    0 Expresses

    0 Mutation Involves

    Phenotype

    Mouse alleles --> Mammalian phenotypes (MP terms)

     

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    3 Publication categories

    Trail: Allele