| Primary Identifier | MGI:6446855 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Gab3 |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 2 was targeted with three shRNA guide sequences (5'-ACACTATCTGGAGTCACTTA-3', 5'-CTACCTAGTAGCCAAGACTG-3', 5'-AGTCATCTGGAAGATGGTGC-3') using CRISPR/Cas9 technology. One founder mouse presented with an insertion of a G nucleotide in exon 2 (c.301_302insG), causing a frameshift and premature termination. |
