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Allele : Cdkn2a<em2Hwl> cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 2, Han-Woong Lee

Primary Identifier	MGI:6449246	Allele Type	Endonuclease-mediated
Attribute String	Modified isoform(s), Null/knockout	Gene	Cdkn2a
Strain of Origin	C57BL/6JBomTac	Is Recombinase	false
Is Wild Type	false

molecularNote

A seven-nucleotide deletion, predicted to produce abnormal 16 AAs before a premature termination codon, was generated by TALEN mediated excision in the C57BL/6J strain.

mutations:
Intragenic deletion

synonyms:
B6-p16<Ink4a> KO,
B6-p16<Ink4a> KO

earliestPublication:
Park BM, et al. (2018) Generation of knockout mouse models of cyclin-dependent kinase inhibitors by engineered nuclease-mediated genome editing. Lab Anim Res 34(4):264-269

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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