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Allele : Rr148<em1Wsa> regulatory region 148; endonuclease-mediated mutation 1, Warren S Alexander

Primary Identifier	MGI:6449636	Allele Type	Endonuclease-mediated
Attribute String	Modified regulatory region	Gene	Rr148
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

The 200 bp core region cEmu of enhancer iEmu, located in an intron between the Igh Cmu constant region segments and Jh joining region segments, was deleted by CRISPR/Cas9 genome editing technology.

mutations:
Intragenic deletion

synonyms:
cEmu<delta>,
cEmu<delta>,
Igh<em1Wsa>,
Igh<em1Wsa>

earliestPublication:
Ng AP, et al. (2020) An Erg-driven transcriptional program controls B cell lymphopoiesis. Nat Commun 11(1):3013

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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