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Allele : Oprm1<tm1.1(cre/GFP)Rpa> opioid receptor, mu 1; targeted mutation 1.1, Richard D Palmiter

Primary Identifier  MGI:6451472 Allele Type  Targeted
Attribute String  Null/knockout, Recombinase, Reporter Gene  Oprm1
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1
Is Recombinase  true Is Wild Type  false
Project Collection  Sanger miRNA knockouts
molecularNote  A cassette encoding Cre:GFP (a Myc-tag and nuclear localization signals at the N-terminus of Cre recombinase, which is fused to green fluorescent protein followed by a SV40 polyadenylation sequence) was inserted just 5' of the initiation codon in the first coding exon of the Oprm1 gene replacing the exon 1 via homologous recombination. The neomycin cassette was excised of through crosses with animals broadly expressing Flp recombinase.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Oprm1<Cre:GFP>,
  • Oprm1<Cre>,
  • Oprm1<Cre>,
  • Oprm1<Cre:GFP>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

10 Publication categories