Primary Identifier | MGI:6456549 | Allele Type | Transgenic |
Attribute String | Epitope tag, Inserted expressed sequence | Gene | Tg(Myh6-Sgk1*K141M)1Anr |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgenic construct contains a hemagluttinin (HA) tagged mutant mouse Sgk1 sequence under the control of the cardiac-specific Myh6 promoter. The KD mutation replaces a lysine at residue 141 (published as 127) for a methionine (K141M), inactivating the kinase (kinase dead - KD). |