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Allele : Mcc<tm1.2Maija> mutated in colorectal cancers; targeted mutation 1.2, Maija Kohonen-Corish

Primary Identifier  MGI:6455801 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Mcc
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 4 was replaced with the following sequences: a loxP site, a partial cDNA (from E330037C1Rik) containing exons 4-19, an FRT site flanked neomycin resistance gene cassette, a second loxP site, exon 4 splice acceptor site, the EGFP reporter gene, and a STOP cassette. The neo cassette was removed through subsequent flp-mediated recombination and the cDNA insert through cre-mediated recombination. This leaves a knockout reporter allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Mcc<delta>,
  • Mcc<delta>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories