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Allele : Tg(Cd3d-CD2)pDarl transgene insertion p, Dan R Littman

Primary Identifier	MGI:6456204	Allele Type	Transgenic
Attribute String	Humanized sequence, Inserted expressed sequence	Gene	Tg(Cd3d-CD2)pDarl
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

A mouse Cd4 minigene consisting of the upstream Cd2 enhancer, the mouse Cd3d promoter, Cd2 5' UTR-containing exon 1, intron 1 (8.6 kb) and the 5' UTR part of the start codon-containing exon 2, was linked to the human CD2 cDNA sequence, followed by SV40 poly(A) signal sequence.

mutations:
Insertion

earliestPublication:
Sawada S, et al. (1994) A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development. Cell 77(6):917-29

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

1 Driven By

2 Publication categories

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