| Primary Identifier | MGI:6456580 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Serinc3 |
| Transmission | Germline | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Cre-mediated excision of the parental Serinc5tm1a(KOMP)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon 3 leaving behind the inserted lacZ reporter sequence. RT-qPCR shows significantly lower mRNA transcript levels in homozygotes. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. |
