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Allele : Iah1<em1Kobam> isoamyl acetate-hydrolyzing esterase 1 homolog; endonuclease-mediated mutation 1, Misato Kobayashi

Primary Identifier	MGI:6456042	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Iah1
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR-targeting deleted 53 bp to create a frameshift and premature termination. Western blot analysis confirmed the absence of protein expression in several tissues.

mutations:
Intragenic deletion

earliestPublication:
Masuya T, et al. (2020) Ablation of Iah1, a candidate gene for diet-induced fatty liver, does not affect liver lipid accumulation in mice. PLoS One 15(5):e0233087

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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