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Allele : Unc80<em2Dren> unc-80, NALCN activator; endonuclease-mediated mutation 2, Dejian Ren

Primary Identifier	MGI:6451181	Allele Type	Endonuclease-mediated
Attribute String	Not Specified	Gene	Unc80
Strain of Origin	(C57BL/6J x SJL/J)F1	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR/Cas9 technology replaced the leucine-encoding codon CTA at position 2654 with a stop codon TAA (L2654*).

mutations:
Nucleotide substitutions

synonyms:
L2654* KI,
L2654* KI

earliestPublication:
Wie J, et al. (2020) Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex. Nat Commun 11(1):3351

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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