| Primary Identifier | MGI:6454350 | Allele Type | Endonuclease-mediated |
| Attribute String | Constitutively active, Humanized sequence | Gene | Stim1 |
| Strain of Origin | (C57BL/6 x CBA)F1 x C57BL/6NTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A chr7:102421471A>T (GRCm38.p4) point mutation was generated using zinc finger nuclease and a repair oligodinucleotide. This mutation changes arginine codon 304 to a tryptophan codon (p.R304W) and is found in Stormorken syndrome patients. Immunohistochemistry experiments showed protein expression from this allele. |
