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Allele : Tg(Thy1/THY1)mhT4Gsv transgene insertion mhT4, Frank Grosveld

Primary Identifier  MGI:6458476 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Thy1/THY1)mhT4Gsv
Strain of Origin  (CBA x C57BL/10)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of a hybrid Thy1 gene which contains 1.5 kb 5' flanking sequences of the murine Thy1 gene, a 5.7 kb EcoRI-ApaI mouse Thy1a (Thy1.1) gene fragment containing the first 4 exons (including exons 1a and 1b) and part of exon 4 that is fused to a 3.4 kb ApaI-EcoRI human THY1 DNA sequence containing the remaining noncoding part of exon IV plus 3' human flanking sequence. High levels of hybrid transgene expression is seen in glomerular podocytes.
  • mutations:
  • Insertion
  • synonyms:
  • mhT4,
  • mhT4
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1 Feature

Genome

2 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories