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Allele : Mafa<tm2Eyc> MAF bZIP transcription factor A; targeted mutation 2, Alain Eychene
Primary Identifier  MGI:6459714 Allele Type  Targeted
Attribute String  Conditional ready Gene  Mafa
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A FRT-flanked PGK-neo selection cassette resides downstream of the polyadenylation signal of the endogenous gene, and loxP sites are present 46 bp upstream of the ATG translation initiation codon and downstream of the neo cassette. The 3' loxP site is followed by the mutated form of Mafa (Mafa-4A) preventing GSK3 phosphorylation of the protein.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Mafa<tm2(4A)Eyc>,
  • Mafa<flox4a>,
  • Mafa<tm2(4A)Eyc>,
  • Mafa<flox4a>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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