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Allele : Zbtb40<em1Clab> zinc finger and BTB domain containing 40; endonuclease-mediated mutation 1, Cheryl Ackert-Bicknell

Primary Identifier  MGI:6454063 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Zbtb40
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  An insertion/deletion mutation was created in the second coding exon of the gene to induce a premature stop codon, limiting full translation of the generated transcript. The translated protein is truncated at the N-terminus by 76 amino acids, lacking the majority of the BTB (protein-protein interaction) domain, with the remainder of the protein intact. This has been confirmed by DNA and RNA sequencing as well as Western blot analysis of protein products.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Zbtb40<mut>,
  • Zbtb40<mut>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele