|  Help  |  About  |  Contact Us

Allele : Ano10<tm1b(EUCOMM)Wtsi> anoctamin 10; targeted mutation 1b, Wellcome Trust Sanger Institute

Primary Identifier  MGI:6456850 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Ano10
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_Bact_P cassette was inserted at position 122088304 of Chromosome 9 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 122091060. The critical exon(s) is/are thus flanked by loxP sites. A reporter knockout mouse was created through subsequent cre-mediated recombination.
  • mutations:
  • Intragenic deletion,
  • Insertion
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories