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Allele : Igk<tm3.1(VRCO1)Nemz> immunoglobulin kappa chain complex; targeted mutation 3.1, David Nemazee
Primary Identifier  MGI:6459233 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Igk
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector was constructed using a loxP-flanked neomycin cassette and the HIV antibody germline-reverted VRC01 sequence including the mature LCDR3 (light chain complementarity determining region 3) to replace the J cluster from Igk. Cre-mediated recombination removed the floxed neo cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • VRC01<gL>,
  • VRC01<gL>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories





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