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Allele : Akt1<tm1Mjl> thymoma viral proto-oncogene 1; targeted mutation 1, Marjorie J Lindhurst

Primary Identifier  MGI:6460299 Allele Type  Targeted
Attribute String  Conditional ready, Reporter Gene  Akt1
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6-Tg(UBC-GFP)30Scha/J)F1
Is Recombinase  false Is Wild Type  false
description  ES cell line = HG3 - (129S6/SvEvTac x C57BL/6-Tg(UBC-GFP)30Scha/J)F1
molecularNote  A G to A nucleotide change at position 49 (c.49G>A) was introduced in exon 3 resulting in a glutamate to lysine substitution at amino acid 17 (p.E17K). In addition, a loxP-flanked lacZ and neomycin resistance gene fusion cassette containing a transcription termination signal was inserted upstream of exon 3. This allele is will only be expressed when cre recombinase is present.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • AKT1<tmfl/Lind>,
  • Akt1<flx>,
  • AKT1<tmfl/Lind>,
  • Akt1<flx>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories