Primary Identifier | MGI:6466536 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tek |
Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NCrl)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LoxP sites were inserted to flank the minimal promoter and exon 1, which contains the start ATG codon and encode the first 17 amino acids. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. Cre-mediated recombination resulted in the deletion of the minimal promoter and exon 1. |