Primary Identifier | MGI:6466546 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cyp26b1 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted in intron 4 and an FRT flanked PGK-neomycin selection cassette folled by a second loxP site was inserted in the 3' untranslated region of exon 6. The selection cassette was subsequently removed by flp expression. Exons 5 and 6 were deleted in the germline via Cre-mediated recombination. |