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Allele : Bscl2<em1Gliu> BSCL2 lipid droplet biogenesis associated, seipin; endonuclease-mediated mutation 1, George Liu

Primary Identifier	MGI:6466589	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Bscl2
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR/Cas9 genome editing technology was used to generate a 701 bp deletion in the gene, including exon 2.

mutations:
Intragenic deletion

synonyms:
Seipin<->,
Seipin<->

earliestPublication:
Gao M, et al. (2020) GPAT3 deficiency alleviates insulin resistance and hepatic steatosis in a mouse model of severe congenital generalized lipodystrophy. Hum Mol Genet 29(3):432-443

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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