Primary Identifier | MGI:6467991 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Vps13b |
Transmission | Germline | Strain of Origin | C57BL/6N |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted into intron 2 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 3. The neo cassette was removed through subsequent flp-mediated recombination. Exon 3 was deleted through subsequent cre-mediated recombination, creating a frameshift in the reading frame. |