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Allele : Del(5Rr78-Rr116)2Tshir deletion, Chr 5, Toshihiko Shiroishi 2

Primary Identifier	MGI:6470875	Allele Type	Endonuclease-mediated
Attribute String	Modified regulatory region	Gene	Del(5Rr78-Rr116)2Tshir
Strain of Origin	C57BL/6JJcl	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR-targeting deleted 118 kb encompassing Shh brain enhancers 2, 3 and 4 (SBE2-SBE4).

mutations:
Intergenic deletion

synonyms:
Rr(FC)<em2Tshir>,
9530036O11Rik<em2Tshir>,
Del(5)1Tshir,
Rr(FC)<em2Tshir>,
delta234,
Del(5)1Tshir,
delta234,
9530036O11Rik<em2Tshir>

earliestPublication:
Sagai T, et al. (2019) SHH signaling mediated by a prechordal and brain enhancer controls forebrain organization. Proc Natl Acad Sci U S A 116(47):23636-23642

1 Feature

Genome

0 Expresses

3 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

2 Publication categories

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