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Allele : Nf1<tm1Luo> neurofibromin 1; targeted mutation 1, Guangbin Luo

Primary Identifier  MGI:6469615 Allele Type  Targeted
Attribute String  Conditional ready, Modified isoform(s) Gene  Nf1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The 5' splice site (5' SS) and polypyrimidine tract associated with exon 23a were mutated to promote inclusion in the final transcript. A neomycin cassette was inserted into the intron downstream of exon 23a and a second loxP site upstream.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Nf1<23aINneo>,
  • Nf1<23aIN>,
  • Nf1<23aIN>,
  • Nf1<23aINneo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories