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Allele : Pik3ca<tm1Rps> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1, Ramon Parsons

Primary Identifier  MGI:6477993 Allele Type  Targeted
Attribute String  Conditional ready Gene  Pik3ca
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 9 was replaced with a floxed splice acceptor/neomycin resistance cassette and a modified exon 9 in which a G to A mutation results in the amino acid substitution of lysine for glutamic acid at position 545 (E545K).
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Pik3ca<E545K>,
  • Pik3ca<E545K>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories