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Allele : Rrm2b<em1Mem> ribonucleotide reductase M2 B (TP53 inducible); endonuclease-mediated mutation 1, Marcy E MacDonald

Primary Identifier	MGI:6489292	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Rrm2b
Strain of Origin	C57BL/6J	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR-targeting deleted 10 bp.

mutations:
Intragenic deletion

synonyms:
Rrm2b_del10,
Rrm2b_del10

earliestPublication:
Loupe JM, et al. (2020) Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out. Hum Mol Genet 29(18):3044-3053

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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