Primary Identifier | MGI:6500762 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Slc26a4 |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated a T to C change at position 707 (c.T707C) resulting in an leucine to proline substitution at residue 236 (L236P). This is the most common mutation found in individuals with Pendred syndrome. |