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Allele : Trp53<tm3.1Thst> transformation related protein 53; targeted mutation 3.1, Thorsten Stiewe
Primary Identifier  MGI:6507841 Allele Type  Targeted
Attribute String  Not Specified Gene  Trp53
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct introduced a mutation (TCC to GCC) resulting in the amino acid substitution of serine with alanine at position 180 (p.S180A) and inserted a loxP site flanked STOP/selection cassette. Cre-mediated recombination removed the STOP/selection cassette.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Trp53<S180A>,
  • Trp53<S180A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories





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