| Primary Identifier | MGI:6507434 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Disc1 |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting construct is designed to delete 4 base pairs (TCTT) in exon 12 of the gene. This deletion is analogous to a deletion found in patients with neuropsychiatric disorders such as schizophrenia. A loxP flanked neomycin (neo) resistance cassette was inserted downstream of the deletion. Germ line, cre mediated recombination removed the neo cassette. |
